Molecular Typing of Pneumococci for Investigation of Linked Cases of Invasive Pneumococcal Disease

Author:

Pichon Bruno1,Moyce Laura1,Sheppard Carmen1,Slack Mary1,Turbitt Deborah2,Pebody Richard3,Spencer David A.4,Edwards Justin5,Krahé Daniel5,George Robert1

Affiliation:

1. Respiratory & Systemic Infection Laboratory, Health Protection Agency Centre for Infections, London

2. North East and Central London Health Protection Unit, Health Protection Agency, London

3. Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency Centre for Infections, London

4. Newcastle upon Tyne Hospitals Foundation NHS Trust, Freeman Hospital, Newcastle upon Tyne

5. Homerton University Hospital, London, United Kingdom

Abstract

ABSTRACT In winter 2007-2008, an outbreak of pediatric pneumonia caused by serotype 5 pneumococci was identified in a northeast London suburb. Variable number of tandem repeat analyses clustered these pneumococci from the other serotype 5 pneumococci in the United Kingdom, highlighting the importance of this discriminative typing method in supporting epidemiological investigations.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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