In vitro antimicrobial susceptibilities of penicillinase-producing and non-penicillinase-producing strains of Neisseria gonorrhoeae isolated in Durban, South Africa

Author:

Coovadia Y M,Ramsaroop U

Abstract

The in vitro susceptibilities of 22 penicillinase-producing and 32 non-penicillinase-producing strains of Neisseria gonorrhoeae to 13 antimicrobial agents, including the new semisynthetic penicillins and cephalosporins, are reported. Ceftriaxone, ceftazidime, and cefotaxime were the most active agents tested; none of them had an MIC of greater than 0.03 micrograms/ml. Amoxycillin plus clavulanic acid and temocillin also showed good activity against both strains of gonococci.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

1. The emergence of penicillinase-producing strains of Neisseria gonorrhoeae in Durban;Coovadia Y. M.;S. Afr. Med. J.,1984

2. National gonorrhoea therapy monitoring study. In vitro antibiotic susceptibility and its correlation with treatment results;Jaffe H. W.;New Engl. J. Med.,1976

3. In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents;Liebowitz L. D.;Antimicrob. Agents Chemother.,1982

4. Neisseria gonorrhoeae strains isolated in Hong Kong: in vitro susceptibility to 13 antibiotics;Ng W. S.;Antimicrob. Agents Chemother.,1981

5. Penicillinase-producing Neisseria gonorrhoeae isolates from different localities in South East Asia: susceptibility to 15 antibiotics;Ng W. S.;Br. J. Vener. Dis.,1983

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