Genome Sequence of “Candidatus Methanomethylophilus alvus” Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens

Author:

Borrel Guillaume1,Harris Hugh M. B.2,Tottey William1,Mihajlovski Agnès1,Parisot Nicolas1,Peyretaillade Eric1,Peyret Pierre1,Gribaldo Simonetta3,O'Toole Paul W.2,Brugère Jean-François1

Affiliation:

1. EA-4678 CIDAM, Conception Ingénierie et Développement de l'Aliment et du Médicament, Clermont Université, Université d'Auvergne, Clermont-Ferrand, France

2. Department of Microbiology and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland

3. Unité de Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, Paris, France

Abstract

ABSTRACT We report the draft genome sequence of “ Candidatus Methanomethylophilus alvus” Mx1201, a methanogen present in the human gut. It was enriched from human feces under anaerobic conditions with methanol as the substrate. Its circular genome, of around 1.7 Mb, contains genes needed for methylotrophic methanogenesis from methanol and tri-, di-, and monomethylamine.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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