The ESCRT-I Subunit Tsg101 Plays Novel Dual Roles in Entry and Replication of Classical Swine Fever Virus

Author:

Liu Chun-chun1,Liu Ya-yun1,Cheng Yan1,Zhang Yun-Na1,Zhang Jin1,Liang Xiao-Dong1,Gao Ya1,Chen Huan1,Baloch Abdul Sattar1,Yang Qian1,Go Yun Young2ORCID,Zhou Bin1ORCID

Affiliation:

1. MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China

2. Department of Infectious Diseases and Public Health, City University of Hong Kong, Hong Kong SAR, China

Abstract

CSF, caused by CSFV, is a World Organization for Animal Health (OIE) notifiable disease and causes significant financial losses to the pig industry globally. The ESCRT machinery plays an important regulatory role in several members of the genera Flavivirus and Hepacivirus within the family Flaviviridae , such as hepatitis C virus, Japanese encephalitis virus, and dengue virus.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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