The Protective Effects of Live and Pasteurized Akkermansia muciniphila and Its Extracellular Vesicles against HFD/CCl4-Induced Liver Injury-Reference-Cited by-同舟云学术

The Protective Effects of Live and Pasteurized Akkermansia muciniphila and Its Extracellular Vesicles against HFD/CCl4-Induced Liver Injury

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Keshavarz Azizi Raftar Shahrbanoo¹²³^ORCID,Ashrafian Fatemeh¹²⁴,Yadegar Abbas³,Lari Arezou⁵,Moradi Hamid Reza⁶,Shahriary Arefeh¹,Azimirad Masoumeh³,Alavifard Helia⁷,Mohsenifar Zhaleh⁸,Davari Mehdi¹²,Vaziri Farzam¹²,Moshiri Arfa⁹¹⁰,Siadat Seyed Davar¹²^ORCID,Zali Mohammad Reza⁹

Affiliation:

1. Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran

2. Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran, Tehran, Iran

3. Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Clinical Research Department, Pasteur Institute of Iran, Tehran, Iran

5. Systems Biomedicine Unit, Pasteur Institute of Iran, Tehran, Iran

6. Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran

7. Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

8. Taleghani Hospital, Department of Pathology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

9. Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

10. Experimental Therapy Unit, Laboratory of Oncology, Giannina Gaslini Children’s Hospital, Genoa, Italy

Abstract

Akkermansia muciniphila , as a member of the gut microbiota, has been proposed as a next-generation probiotic. Liver fibrosis is the main determinant of liver dysfunction and mortality in patients with chronic liver disease.

Funder

SBUMS | Research Institute for Gastroenterology and Liver Diseases

Pasteur Institute of Iran

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00484-21

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