Saliva is Comparable to Nasopharyngeal Swabs for Molecular Detection of SARS-CoV-2-Reference-Cited by-同舟云学术

Saliva is Comparable to Nasopharyngeal Swabs for Molecular Detection of SARS-CoV-2

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Callahan Cody¹²,Ditelberg Sarah²,Dutta Sanjucta²,Littlehale Nancy³,Cheng Annie²,Kupczewski Kristin²,McVay Danielle²,Riedel Stefan²³⁴^ORCID,Kirby James E.²³⁴^ORCID,Arnaout Ramy²⁵³⁴^ORCID

Affiliation:

1. Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

2. Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

3. Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

4. Harvard Medical School, Boston, Massachusetts, USA

5. Division of Clinical Informatics, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

Abstract

In general, the most accurate COVID-19 testing is hands-on and uncomfortable, requiring trained staff and a “brain-tickling” nasopharyngeal swab. Saliva would be much easier on both fronts, since patients could collect it themselves, and it is after all just spit.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00162-21

Reference23 articles.

1. A combined oropharyngeal/nares swab is a suitable alternative to nasopharyngeal swabs for the detection of SARS-CoV-2

2. Comparison of Abbott ID Now, DiaSorin Simplexa, and CDC FDA Emergency Use Authorization Methods for the Detection of SARS-CoV-2 from Nasopharyngeal and Nasal Swabs from Individuals Diagnosed with COVID-19

3. Saliva as an Alternate Specimen Source for Detection of SARS-CoV-2 in Symptomatic Patients Using Cepheid Xpert Xpress SARS-CoV-2

4. Self-Collected Oral Fluid and Nasal Swabs Demonstrate Comparable Sensitivity to Clinician Collected Nasopharyngeal Swabs for Covid-19 Detection

5. Sensitivity of Nasopharyngeal, Nasal and Throat Swab for the Detection of SARS-CoV-2

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