Carbapenem-Resistant Gram-Negative Bacterial Infections in Children-Reference-Cited by-同舟云学术

Carbapenem-Resistant Gram-Negative Bacterial Infections in Children

Published:2020-02-21 Issue:3 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Aguilera-Alonso David¹,Escosa-García Luis²,Saavedra-Lozano Jesús³,Cercenado Emilia⁴,Baquero-Artigao Fernando²

Affiliation:

1. Pediatric Infectious Diseases Unit, Gregorio Marañón Hospital, Madrid, Spain

2. Department of Infectious Diseases and Tropical Pediatrics, La Paz Hospital, Madrid, Spain

3. Pediatric Infectious Diseases Unit, Gregorio Marañón Hospital, Complutense University, Madrid, Spain

4. Department of Infectious Diseases and Clinical Microbiology, Gregorio Marañón Hospital, Complutense University, Madrid, Spain

Abstract

Carbapenem-resistant organisms (CRO) are a major global public health threat. Enterobacterales hydrolyze almost all β-lactams through carbapenemase production. Infections caused by CRO are challenging to treat due to the limited number of antimicrobial options. This leads to significant morbidity and mortality. Over the last few years, several new antibiotics effective against CRO have been approved.

Funder

MEC | Instituto de Salud Carlos III

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02183-19

Reference154 articles.

1. Carbapenem-Resistant Enterobacteriaceae Infections in Children

2. Treatment of Multidrug-Resistant Gram-Negative Infections in Children

3. Treatment of Infections Caused by Extended-Spectrum-Beta-Lactamase-, AmpC-, and Carbapenemase-Producing Enterobacteriaceae