Structural Insight into the Role of the PAS Domain for Signal Transduction in Sensor Kinase BvgS-Reference-Cited by-同舟云学术

Structural Insight into the Role of the PAS Domain for Signal Transduction in Sensor Kinase BvgS

Published:2021-04-08 Issue:9 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Dupré Elian¹,Clantin Bernard²,Yuan Youhua¹,Lecher Sophie¹,Lesne Elodie¹,Antoine Rudy¹,Villeret Vincent²,Jacob-Dubuisson Françoise¹^ORCID

Affiliation:

1. University Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017, CIIL-Center for Infection and Immunity of Lille, Lille, France

2. U1167-RID-AGE University Lille, Inserm, CHU Lille, Institut Pasteur de Lille-CNRS ERL 9002-Integrative Structural Biology-BP 70478, Villeneuve d'Ascq Cedex, France

Abstract

The whooping cough agent Bordetella pertussis colonizes the human respiratory tract by using virulence factors coregulated by the sensory transduction system BvgAS. BvgS is a model for a family of sensor kinase proteins, some of which are found in important bacterial pathogens.

Funder

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00614-20

Reference49 articles.

1. Sensor domains of two-component regulatory systems

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5. Biological Insights from Structures of Two-Component Proteins

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