Molecular Basis of the Leishmanicidal Activity of the Antidepressant Sertraline as a Drug Repurposing Candidate-Reference-Cited by-同舟云学术

Molecular Basis of the Leishmanicidal Activity of the Antidepressant Sertraline as a Drug Repurposing Candidate

Published:2018-12 Issue:12 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Lima Marta L.¹²³^ORCID,Abengózar María A.¹,Nácher-Vázquez Montserrat¹^ORCID,Martínez-Alcázar María P.²,Barbas Coral²^ORCID,Tempone Andre G.³^ORCID,López-Gonzálvez Ángeles²^ORCID,Rivas Luis¹^ORCID

Affiliation:

1. Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain

2. Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad CEU San Pablo, Boadilla del Monte, Madrid, Spain

3. Centre for Parasitology and Mycology, Institute Adolfo Lutz, São Paulo, São Paulo, Brazil

Abstract

Drug repurposing affords the implementation of new treatments at a moderate cost and under a faster time-scale. Most of the clinical drugs against Leishmania share this origin.

Funder

Red de Enfermedades Tropicales Fondo de Investigaciones Sanitarias-ISCIII-FEDER

Plan Estatal de I+D+i Ministerio de Economía y Competitividad. FEDER

Consejo Superior de Investigaciones Científicas

Sao Paulo State Research Foundation

EADS-CASA/Brazilian Air Force (FAB) Mobility Program

Coordenaçao de Aperfeiçoamento de Pessoal de Nivel Superior

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link