Comprehensive Transcriptome Profiles of Streptococcus mutans UA159 Map Core Streptococcal Competence Genes-Reference-Cited by-同舟云学术

Comprehensive Transcriptome Profiles of Streptococcus mutans UA159 Map Core Streptococcal Competence Genes

Published:2016-04-26 Issue:2 Volume:1 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Khan R.¹,Rukke H. V.¹,Høvik H.¹,Åmdal H. A.¹,Chen T.²,Morrison D. A.³,Petersen F. C.¹

Affiliation:

1. Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway

2. The Forsyth Institute, Cambridge, Massachusetts, USA

3. Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA

Abstract

S. mutans has the hard surfaces of the oral cavity as its natural habitat, where it depends on its ability to form biofilms in order to survive. The comprehensive identification of S. mutans regulons activated in response to peptide pheromones provides an important basis for understanding how S. mutans can transition from individual to social behavior. Our study placed 27 of the 29 transcripts activated during competence within three major regulons and revealed a core set of 27 panstreptococcal competence-activated genes within the SigX regulon.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00038-15

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