First Linezolid-Resistant Clinical Isolates of Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

First Linezolid-Resistant Clinical Isolates of Mycobacterium tuberculosis

Published:2007-04 Issue:4 Volume:51 Page:1534-1536
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Richter Elvira¹,Rüsch-Gerdes Sabine¹,Hillemann Doris¹

Affiliation:

1. Forschungszentrum Borstel, National Reference Center for Mycobacteria, D-23845 Borstel, Germany

Abstract

ABSTRACT Linezolid resistance was found in 4 (1.9%) of 210 multidrug-resistant Mycobacterium tuberculosis strains. The MICs of linezolid were 4 μg/ml (one strain) and 8 μg/ml (three strains). Since no mutations were detected in potential target genes, the mechanism of resistance remains unclear.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01113-06

Reference12 articles.

1. Bozdogan, B., and P. C. Appelbaum. 2004. Oxazolidinones: activity, mode of action, and mechanism of resistance. Int. J. Antimicrob. Agents23:113-119.

2. Molecular Basis of Intrinsic Macrolide Resistance in the Mycobacterium tuberculosis Complex

3. Pharmacokinetics and Tissue Penetration of Linezolid following Multiple Oral Doses

4. Rapid Detection of Mycobacterium tuberculosis Beijing Genotype Strains by Real-Time PCR

5. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

Cited by 92 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides;2024-08-14

2. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides;2024-08-14

3. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides;2024-04-12

4. A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides;2023-11-16

5. Investigation of genomic mutations and their association with phenotypic resistance to new and repurposed drugs in Mycobacterium tuberculosis complex clinical isolates;Journal of Antimicrobial Chemotherapy;2023-09-23