Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis-Reference-Cited by-同舟云学术

Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis

Published:2007-09 Issue:9 Volume:51 Page:3367-3370
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Swarup Vivek¹,Ghosh Joydeep¹,Ghosh Soumya¹,Saxena Amit¹,Basu Anirban¹

Affiliation:

1. National Brain Research Centre, Manesar, Haryana, India

Abstract

ABSTRACT Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads ( P < 0.001) and proinflammatory cytokine levels ( P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00041-07

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