The Role of 17β-Estrogen in Escherichia coli Adhesion on Human Vaginal Epithelial Cells via FAK Phosphorylation

Author:

Liu Xia12,Luan Ting1,Zhou Wanqing3,Yan Lina1,Qian Hua2,Mao Pengyuan1,Jiang Lisha14,Liu Jingyan1,Rui Can1,Wang Xinyan1,Li Ping1,Zeng Xin1ORCID

Affiliation:

1. Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, People’s Republic of China

2. Department of Obstetrics and Gynecology, Jiangsu Taizhou People's Hospital, Taizhou, Jiangsu, People’s Republic of China

3. Department of Clinical Laboratory, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, People’s Republic of China

4. Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Medical University Of Anhui, Hefei, People’s Republic of China

Abstract

Estrogen, the predominant sex hormone, has been found to be related to the occurrence of vaginal infectious diseases. However, its role in the occurrence and development of bacterial vaginitis caused by Escherichia coli is still unclear.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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