Pharmacological Evaluation of Cefaclor in Volunteers-Reference-Cited by-同舟云学术

Pharmacological Evaluation of Cefaclor in Volunteers

Published:1978-09 Issue:3 Volume:14 Page:454-456
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hodges Glenn R.¹,Liu Chien²,Hinthorn Daniel R.²,Harms Jane L.²,Dworzack David L.²

Affiliation:

1. Medical Service, Veterans Administration Hospital, Kansas City, Missouri 64128

2. Division of Infectious Diseases, Department of Medicine, University of Kansas Medical Center, College of Health Sciences, Kansas City, Kansas 66103,

Abstract

The plasma and urine concentrations of cefaclor were measured after oral administration of single and multiple doses to volunteers. Cefaclor was rapidly absorbed, rapidly excreted in the urine, well tolerated without toxicity, and failed to accumulate in the plasma with chronic dosing.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.14.3.454

Reference7 articles.

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4. In vitro studies with cefaclor, a new oral cephalosporin;Sanders C. C.;Antimicrob. Agents Chemother.,1977

5. In vitro activity of cefaclor, a new orally administered cephalosporin antibiotic;Santoro J.;Antimicrob. Agents Chemother.,1977

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