Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator-Reference-Cited by-同舟云学术

Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator

Published:2023-06-27 Issue:3 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Liu Chang¹²,Zhang Hua¹³²,Peng Xian¹²,Blackledge Meghan S.⁴,Furlani Robert E.⁴,Li Haoting⁴,Su Zhaoming⁴,Melander Roberta J.⁴,Melander Christian⁴,Michalek Suzanne³,Wu Hui¹³²

Affiliation:

1. Department of Pediatric Dentistry, University of Alabama at Birmingham Schools of Dentistry and Medicine, Birmingham, Alabama, USA

2. Department of Microbiology, University of Alabama at Birmingham Schools of Dentistry and Medicine, Birmingham, Alabama, USA

3. Department of Integrative Biomedical & Diagnostic Sciences, Oregon Health & Science University School of Dentistry, Portland, Oregon, USA

4. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA

Abstract

Antibiotic resistance is a major public health issue due to the growing lack of effective anti-infective therapeutics. New alternatives to treat and prevent biofilm-driven microbial infections, which exhibit high tolerance to clinically available antibiotics, are urgently needed.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00137-23

Reference72 articles.

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