Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity-Reference-Cited by-同舟云学术

Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Lagatie Ole¹^ORCID,Lauwers Dax¹,Singh Harvinder¹,Vanroye Fien²^ORCID,Stieh Daniel J.³,Vingerhoets Johan⁴,Lavreys Ludo³,Oriol-Mathieu Valérie³,Colón Will¹,Verhofstede Chris⁵,Vercauteren Koen²,Van den Bossche Dorien²,Pau Maria Grazia³

Affiliation:

1. Johnson & Johnson Global Public Health Research & Development, Beerse, Belgium

2. Institute of Tropical Medicine, Antwerp, Belgium

3. Janssen Vaccines and Prevention B.V., Leiden, The Netherlands

4. Janssen Research & Development, Beerse, Belgium

5. Ghent University, Ghent, Belgium

Abstract

While the detection of HIV infection is accomplished by several methods, the most common are serological tests that detect host antibodies produced in response to viral infection. However, the use of current serological tests may present a significant challenge to the adoption of an HIV vaccine in the future because the antibodies to HIV antigens detected in currently available tests also tend to be included as antigens in the HIV vaccines in development.

Funder

Janssen

Flanders Innovation & Entrepreneurship

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00715-23

Reference34 articles.

1. UNAIDS. 2020. UNAIDS data 2020. https://www.unaids.org/sites/default/files/media_asset/2020_aids-data-book_en.pdf.

2. Comparison of four anti-HIV screening assays which belong to different test generations;Dopel SH;Eur J Clin Chem Clin Biochem,1991

3. Evaluation of a dipstick method for the detection of human immunodeficiency virus infection

4. Comparing modified and plain peptide linked enzyme immunosorbent assay (ELISA) for detection of human immunodeficiency virus type-1 (HIV-1) and type-2 (HIV-2) antibodies

5. Synthetic Peptides in the Diagnosis of HIV Infection

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