Zinc-Based Nanoparticles Reduce Bacterial Biofilm Formation

Author:

Bianchini Fulindi Rafael1,Domingues Rodrigues Juliana1,Lemos Barbosa Thulio Wliandon2,Goncalves Garcia Ariana D.3,de Almeida La Porta Felipe4,Pratavieira Sebastião5,Chiavacci Leila Aparecida2,Pessoa Araújo Junior João6,da Costa Paulo Inácio1ORCID,Martinez Luis R.3789ORCID

Affiliation:

1. Departments of Clinical Analysis, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil

2. Departments of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil

3. Department of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA

4. Department of Chemistry, Federal Technological University of Paraná (UTFPR), Londrina, Paraná, Brazil

5. São Carlos Physics Department, University of São Paulo, São Carlos, São Paulo, Brazil

6. Biotechnology Institute, São Paulo State University, Botucatu, São Paulo, Brazil

7. Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA

8. Center for Immunology and Transplantation, University of Florida, Gainesville, Florida, USA

9. Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, Florida, USA

Abstract

Zinc (Zn)-based nanoparticles (NPs) can be potentially used in medical and food preservation applications. As proof of principle, we investigated the bactericidal and antibiofilm activity of zinc oxide (ZnO) and zinc sulfide (ZnS) NPs against medically important bacteria.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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