Metagenome-Assembled Genomes Reveal Mechanisms of Carbohydrate and Nitrogen Metabolism of Schistosomiasis-Transmitting Vector Biomphalaria Glabrata

Author:

Du Shuling12,Sun Xi234,Zhang Jingxiang13,Lin Datao234,Chen Runzhi13,Cui Ying13,Xiang Suoyu23,Wu Zhongdao234ORCID,Ding Tao124ORCID

Affiliation:

1. Department of Immunology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

2. Key Laboratory of Tropical Disease Control, Ministry of Education, Sun Yat-sen University, Guangzhou, China

3. Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

4. Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou, China

Abstract

The spread of aquatic gastropod Biomphalaria glabrata , an intermediate host of Schistosoma mansoni , exacerbates the burden of schistosomiasis disease worldwide. This study provides insights into the importance of microbiome for basic biological activities of freshwater snails, and offers a valuable microbial genome resource to fill the gap in the analysis of the snail-microbiota-parasite relationship.

Funder

111 Project

Guangdong Key Area Research and Development Program

Sun Yat-sen University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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