Construction and Analysis of the Complete Genome Sequence of Leprosy Agent Mycobacterium lepromatosis-Reference-Cited by-同舟云学术

Construction and Analysis of the Complete Genome Sequence of Leprosy Agent Mycobacterium lepromatosis

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Silva Francisco J.¹²^ORCID,Santos-Garcia Diego³^ORCID,Zheng Xiaofeng⁴,Zhang Li⁴,Han Xiang Y.⁵^ORCID

Affiliation:

1. Institute for Integrative Systems Biology (I2SysBio), University of Valencia and CSIC, Paterna, Spain

2. Genomics and Health Area, Foundation for the Promotion of Sanitary and Biomedical Research, Valencia, Spain

3. Laboratory of Biometry and Evolutionary Biology UMR CNRS, University of Lyon, Villeurbanne, France

4. Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

5. Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Abstract

Leprosy is a dreaded infection that still affects millions of people worldwide. Mycobacterium lepromatosis is a recently recognized cause in addition to the well-known Mycobacterium leprae . M. lepromatosis is likely specific for diffuse lepromatous leprosy, a severe form of the infection and endemic in Mexico. This study constructed and annotated the complete genome sequence of M. lepromatosis FJ924 and performed comparative genomic analyses with related mycobacteria.

Funder

HHS | NIH | National Cancer Institute

Ministerio de Ciencia, Innovación y Universidades

Generalitat Valenciana

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01692-21

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