Comparison of Performances of GeneXpert MTB/RIF, Bactec MGIT 960, and Bactec Myco/F Systems in Detecting Mycobacterium tuberculosis in Biopsy Tissues: a Retrospective Study

Author:

Zhao Jiankang12,Pu Danni123,Zhang Yulin12,Qu Jiuxin4,Lu Binghuai12ORCID,Cao Bin12356ORCID

Affiliation:

1. Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, National Center for Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China

2. Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China

3. Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

4. Department of Clinical Laboratory, Shenzhen Third People’s Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Guangdong Provincial Clinical Research Center for Infectious Diseases (Tuberculosis), National Clinical Research Center for Infectious Diseases, Shenzhen, Guangdong, China

5. Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, China

6. Department of Respiratory Medicine, Capital Medical University, Beijing, China

Abstract

Mycobacterium tuberculosis (MTB) poses a severe threat to public health worldwide. The diagnosis of tuberculosis is challenging due to the low load of the microorganism in samples.

Funder

National High Level Hospital Clinical Research Funding

MOST | National Major Science and Technology Projects of China

Shenzhen Science and Technology Innovation Commission | Sanming Project of Medicine in Shenzhen

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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