Evaluation of Rapid Immunochromatographic Tests for the Direct Detection of Extended Spectrum Beta-Lactamases and Carbapenemases in Enterobacterales Isolated from Positive Blood Cultures

Author:

Keshta Ahmed S.12,Elamin Nazik1,Hasan Mohammad Rubayet13ORCID,Pérez-López Andrés13,Roscoe Diane1,Tang Patrick13,Suleiman Mohammed1ORCID

Affiliation:

1. Sidra Medicine, Doha, Qatar

2. School of Medicine, Royal College of Surgeons in Ireland–Bahrain, Busaiteen, Kingdom of Bahrain

3. Weill Cornell Medical College in Qatar, Doha, Qatar

Abstract

The incidence of bloodstream infections (BSI) with extended spectrum beta-lactamase (ESBL) producing and carbapenemase producing Enterobacterales (CPE) is increasing at an alarming rate, for which only limited therapeutic options remain available. Rapid identification of these bacteria along with their antibiotic resistance mechanisms in positive blood cultures with Gram-negative bacteria will allow for early initiation of effective therapy and limit the overuse of broad-spectrum antibiotics in BSI (1).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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