Alginate Alleviates Dextran Sulfate Sodium-Induced Colitis by Promoting Bifidobacterium animalis and Intestinal Hyodeoxycholic Acid Synthesis in Mice-Reference-Cited by-同舟云学术

Alginate Alleviates Dextran Sulfate Sodium-Induced Colitis by Promoting Bifidobacterium animalis and Intestinal Hyodeoxycholic Acid Synthesis in Mice

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Pi Yu¹²,Zhang Xiangyu¹,Wu Yujun¹,Wang Zhenyu¹,Bai Yu¹,Liu Xiaoyi¹,Han Dandan¹^ORCID,Zhao Jinbiao¹^ORCID,Tobin Isabel³,Zhao Jiangchao⁴^ORCID,Zhang Guolong³,Wang Junjun¹^ORCID

Affiliation:

1. State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China

2. Key Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing, China

3. Department of Animal and Food Sciences, Oklahoma State University, Stillwater, Oklahoma, USA

4. Department of Animal Science, Division of Agriculture, University of Arkansas, Fayetteville, Arkansas, USA

Abstract

ALG has been shown to ameliorate inflammatory bowel disease (IBD), but little is known about the mechanism of its anti-inflammatory action. This study was the first to demonstrate that ALG provided a preventive effect against colitis in an intestinal microbiota-dependent manner.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02979-22

Reference69 articles.

1. Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

2. Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

3. Gut microbiome structure and metabolic activity in inflammatory bowel disease