Baicalein Resensitizes Multidrug-Resistant Gram-Negative Pathogens to Doxycycline-Reference-Cited by-同舟云学术

Baicalein Resensitizes Multidrug-Resistant Gram-Negative Pathogens to Doxycycline

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Yuhang¹²^ORCID,Su Junfeng¹,Zhou Ziyan²,Yang Jie¹³,Liu Wenjuan⁴,Zhang Yafen⁴,Zhang Pengyu¹²,Guo Tingting¹²³,Li Guocai¹²³⁴^ORCID

Affiliation:

1. Department of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, People’s Republic of China

2. Jiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Yangzhou, People’s Republic of China

3. Jiangsu Key Laboratory of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, People’s Republic of China

4. Laboratory Department, Affiliated Hospital of Yangzhou University, Yangzhou, People’s Republic of China

Abstract

Doxycycline is an important broad-spectrum tetracycline antibiotic used for treating multiple human infections, but its resistance rates are recently rising globally. Thus, new agents capable of boosting the effectiveness of doxycycline need to be discovered.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04702-22

Reference59 articles.

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