Divergent Effects of Peptidoglycan Carboxypeptidase DacA on Intrinsic β-Lactam and Vancomycin Resistance-Reference-Cited by-同舟云学术

Divergent Effects of Peptidoglycan Carboxypeptidase DacA on Intrinsic β-Lactam and Vancomycin Resistance

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Park Si Hyoung¹,Choi Umji¹,Ryu Su-Hyun²,Lee Han Byeol¹,Lee Jin-Won²,Lee Chang-Ro¹³

Affiliation:

1. Department of Biological Sciences, Myongji University, Yongin, Gyeonggido, Republic of Korea

2. Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea

3. The Natural Science Research Institute, Myongji University, Yongin, Gyeonggido, Republic of Korea

Abstract

Bacterial PG hydrolases play important roles in various aspects of bacterial physiology, including cytokinesis, PG synthesis, quality control of PG, PG recycling, and stress adaptation. Of all the PG hydrolases, the role of PG carboxypeptidases is poorly understood, especially regarding their impacts on antibiotic resistance.

Funder

Basic Science Research Program

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01734-22

Reference55 articles.

1. Murein (peptidoglycan) structure, architecture and biosynthesis in Escherichia coli

2. Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

3. Cell Wall Hydrolases in Bacteria: Insight on the Diversity of Cell Wall Amidases, Glycosidases and Peptidases Toward Peptidoglycan