Impaired Humoral Immunity Identified in Inactivated SARS-CoV-2 Vaccine Recipients without Anti-Spike RBD Antibodies-Reference-Cited by-同舟云学术

Impaired Humoral Immunity Identified in Inactivated SARS-CoV-2 Vaccine Recipients without Anti-Spike RBD Antibodies

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Sun Ting¹,Wang Yuchen¹,Song Xiaoyu¹,Li Ruili²,Mei Fanghua³,Yang Mengliu¹,Huang Xiaojie⁴,Li Yan⁵^ORCID,Zhou Xuwei¹,Wang Haoyu¹,Li Wendong¹,Li Jing¹,Wang Lu¹,Shi Wei¹,Cai Kun³,Li Hongjun⁶,Zhang Jing¹^ORCID

Affiliation:

1. Key Laboratory for Biomechanics and Mechanobiology of the Ministry of Education, Beijing Advanced Innovation Centre for Biomedical Engineering, School of Engineering Medicine, Beihang University, Beijing, China

2. Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China

3. Hubei Center for Disease Control and Prevention, Wuhan, China

4. Clinical and Research Center for Infectious Diseases, Beijing You An Hospital, Capital Medical University, Beijing, China

5. Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

6. Department of Radiology, Beijing You An Hospital, Capital Medical University, Beijing, China

Abstract

Our study illustrates the immune responses engaged by encountering antigen, highlighting the critical roles of B-cell activating humoral immunity in the body’s antibody production.

Funder

Youth Thousand Scholar Program of China

Program for High-Level Overseas Talents, Beihang University

Young Talent Investigator Grant

Beijing YouAn Hospital Project for COVID-19

Beijing Excellent Talent Plan

Beijing National Science Foundation

YouAn Medical Development Project of COVID-19 Emergency Prevention and Control Public

Beijing Natural Science Foundation

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Chinese Institute for Brain Research