Identifying SARS-CoV-2 Variants of Concern through Saliva-Based RT-qPCR by Targeting Recurrent Mutation Sites-Reference-Cited by-同舟云学术

Identifying SARS-CoV-2 Variants of Concern through Saliva-Based RT-qPCR by Targeting Recurrent Mutation Sites

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ham Rachel E.¹^ORCID,Smothers Austin R.¹²,Che Rui¹³,Sell Keegan J.¹,Peng Congyue Annie¹^ORCID,Dean Delphine¹²^ORCID

Affiliation:

1. Center for Innovative Medical Devices and Sensors (REDDI Lab), Clemson University, Clemson, South Carolina, USA

2. Department of Bioengineering, Clemson University, Clemson, South Carolina, USA

3. Department of Genetics and Biochemistry, Clemson University, Clemson, South Carolina, USA

Abstract

SARS-CoV-2 variants of concern and their many sublineages can be characterized by mutations present within their genetic sequences. These mutations can provide selective advantages such as increased transmissibility and antibody evasion, which influences public health recommendations such as mask mandates, quarantine requirements, and treatment regimens.

Funder

South Carolina Governor and Joint Bond Review Committee

Clemson University

HHS | National Institutes of Health

National Science Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00797-22

Reference45 articles.