Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics-Reference-Cited by-同舟云学术

Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xu Ling-Dong¹,Zhang Fei²,Chen Chu¹,Peng Lei¹,Luo Wen-Ting¹,Chen Ruiai³,Xu Pinglong²,Huang Yao-Wei¹^ORCID

Affiliation:

1. Department of Veterinary Medicine, Zhejiang University, Hangzhou, China

2. MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

3. Zhaoqing Branch Center of Guangdong Laboratory for Lingnan Modern Agricultural Science and Technology, Zhaoqing, Guangdong, China

Abstract

HEV infects >20 million people annually, causing acute viral hepatitis as well as chronic hepatitis, neurological diseases, and pregnancy-associated high mortality, which require therapeutic intervention. The HEV antiviral research is largely limited by the lack of a convenient small animal model.

Funder

Guangdong Major Project of Basic and Applied Basic Research

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02193-21

Reference58 articles.

1. Hepatitis E virus

2. Hepatitis E virus: advances and challenges