Plasmodium falciparum Gametes and Sporozoites Hijack Plasmin and Factor H To Evade Host Complement Killing-Reference-Cited by-同舟云学术

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Plasmodium falciparum Gametes and Sporozoites Hijack Plasmin and Factor H To Evade Host Complement Killing

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ernest Medard¹,Rosa Thiago F. A.²,Pala Zarna Rajeshkumar¹,Kudyba Heather M.¹,Sweeney Brendan¹,Reiss Timo²,Pradel Gabriele²,Vega-Rodríguez Joel¹^ORCID

Affiliation:

1. Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA

2. Division of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Aachen, Germany

Abstract

Current approaches to control malaria are complicated by the development of antimalarial-resistant parasites and insecticide-resistant vectors. Vaccines that block transmission to mosquitoes and humans are a plausible alternative to overcome these setbacks.

Funder

European Molecular Biology Organization

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04493-22

Reference32 articles.

1. The complement system;Taran LD;Biokhimiia,1993

2. The human complement system

3. Plasmodium falciparum

4. Plasmodium species: master renovators of their host cells

5. Plasmodium berghei: Sporozoites are sensitive to human serum but not susceptible host serum

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