What’s the Matter with MICs: Bacterial Nutrition, Limiting Resources, and Antibiotic Pharmacodynamics-Reference-Cited by-同舟云学术

What’s the Matter with MICs: Bacterial Nutrition, Limiting Resources, and Antibiotic Pharmacodynamics

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Berryhill Brandon A.¹²,Gil-Gil Teresa¹³⁴,Manuel Joshua A.¹,Smith Andrew P.¹,Margollis Ellie⁵,Baquero Fernando⁶^ORCID,Levin Bruce R.¹^ORCID

Affiliation:

1. Department of Biology, Emory University, Atlanta, Georgia, USA

2. Program in Microbiology and Molecular Genetics, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA

3. Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

4. Programa de Doctorado en Biociencias Moleculares, Universidad Autónoma de Madrid, Madrid, Spain

5. Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

6. Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, and Centro de Investigación Médica en Red, Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

Abstract

For studies of antibiotics and how they work, the most-often used measurement of drug efficacy is the MIC. The MIC is the concentration of an antibiotic needed to inhibit bacterial growth.

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Fulbright Association

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04091-22

Reference42 articles.

1. Application of pharmacokinetics and pharmacodynamics to antimicrobial therapy of respiratory tract infections

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