5′ Untranslated mRNA Regions Allow Bypass of Host Cell Translation Inhibition by Legionella pneumophila-Reference-Cited by-同舟云学术

5′ Untranslated mRNA Regions Allow Bypass of Host Cell Translation Inhibition by Legionella pneumophila

Published:2022-11-17 Issue:11 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Lipo Erion¹²,Asrat Seblewongel³²,Huo Wenwen²,Sol Asaf²,Fraser Christopher S.⁴,Isberg Ralph R.²^ORCID

Affiliation:

1. Program in Genetics, Tufts University School of Medicine, Boston, Massachusetts, USA

2. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

3. Program in Molecular Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

4. Department of Molecular and Cellular Biology, University of California, Davis, California, USA

Abstract

Legionella pneumophila grows within membrane-bound vacuoles in alveolar macrophages during human disease. Pathogen manipulation of the host cell is driven by bacterial proteins translocated through a type IV secretion system (T4SS).

Funder

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00179-22

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5. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae.

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