A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions

Author:

Blanchard Adam M.1ORCID,Staley Ceri E.1,Shaw Laurence2,Wattegedera Sean R.3,Baumbach Christina-Marie4,Michler Jule K.4,Rutland Catrin1,Back Charlotte1,Newbold Nerissa1,Entrican Gary3,Tötemeyer Sabine1

Affiliation:

1. School of Veterinary Medicine and Science, University of Nottingham, Loughborough, Leicestershire, United Kingdom

2. School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

3. Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, Scotland

4. Institute of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany

Abstract

Footrot is a polymicrobial infectious disease in sheep causing severe lameness, leading to one of the industry’s largest welfare problems. The complex etiology of footrot makes in situ or in vitro investigations difficult.

Funder

Rural and Environment Science and Analytical Services Division

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference69 articles.

1. Factors associated with changes of state of foot conformation and lameness in a flock of sheep

2. Foot-rot in sheep: a transmissible disease due to infection with Fusiformis nodosus (n. sp.). Studies on its cause, epidemiology, and control;Beveridge W;Bull Counc Sci Ind Res Aust,1941

3. A STUDY OF SPIROCHAETA PENORTHA (N.SP.) ISOLATED FROM FOOT-ROT IN SHEEP

4. The aetiology and pathogenesis of ovine foot-rot

5. An alum-treated vaccine for the control of foot-rod in sheep

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