The Likelihood of Developing a Carbapenem-Resistant Enterobacteriaceae Infection during a Hospital Stay

Author:

Tamma Pranita D.1,Kazmi Abida2,Bergman Yehudit2,Goodman Katherine E.3,Ekunseitan Ernest1,Amoah Joe1,Simner Patricia J.2

Affiliation:

1. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

2. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

3. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

Abstract

Of 1,455 unique patients in U.S. intensive care units (ICUs), 4% were rectally colonized with CRE on admission. A total of 297 patients were initially negative for carbapenem-resistant Enterobacteriaceae (CRE) and remained in the ICU long enough to contribute additional swabs; 22% of these patients had a subsequent CRE-positive swab, with a median time to CRE colonization of 13 days (interquartile range, 7 to 21 days).

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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