Risk Factors for Colistin Resistance among Gram-Negative Rods and Klebsiella pneumoniae Isolates-Reference-Cited by-同舟云学术

Risk Factors for Colistin Resistance among Gram-Negative Rods and Klebsiella pneumoniae Isolates

Published:2018-09 Issue:9 Volume:56 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Richter Stefan E.¹²,Miller Loren³,Uslan Daniel Z.⁴,Bell Douglas⁵,Watson Karol²⁶,Humphries Romney⁷,McKinnell James A.³

Affiliation:

1. Department of Pulmonology and Critical Care Medicine, University of California, Los Angeles, Los Angeles, California, USA

2. NIH BD2K Center of Excellence at UCLA, University of California, Los Angeles, Los Angeles, California, USA

3. Infectious Disease Clinical Outcome Research Unit, Los Angeles Biomedical Research Institute at Harbor-UCLA, Los Angeles, California, USA

4. Department of Infectious Disease, University of California, Los Angeles, Los Angeles, California, USA

5. Department of Internal Medicine, University of California, Los Angeles, Los Angeles, California, USA

6. Department of Cardiology, University of California, Los Angeles, Los Angeles, California, USA

7. Department of Pathology & Laboratory Medicine, University of California, Los Angeles, Los Angeles, California, USA

Abstract

Infections due to colistin-resistant (Col r ) Gram-negative rods (GNRs) and colistin-resistant Klebsiella pneumoniae isolates in particular result in high associated mortality and poor treatment options. To determine the risk factors for recovery on culture of Col r GNRs and Col r K. pneumoniae , analyses were chosen to aid decisions at two separate time points: the first when only Gram stain results are available without any bacterial species information (corresponding to the Col r GNR model) and the second when organism identification is performed but prior to reporting of antimicrobial susceptibility testing results (corresponding to the Col r K. pneumoniae model).

Funder

HHS | NIH | National Center for Advancing Translational Sciences

HHS | NIH | NIH Clinical Center

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00149-18

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