Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis

Author:

Zhou Yao12,Yan Kaizhou3,Qin Qijian1,Raimi Olawale G.3,Du Chao12,Wang Bin1,Ahamefule Chukwuemeka Samson1,Kowalski Bartosz3,Jin Cheng14ORCID,van Aalten Daan M. F.3,Fang Wenxia12ORCID

Affiliation:

1. Guangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciences, Nanning, Guangxi, China

2. College of Life Science and Technology, Guangxi University, Nanning, Guangxi, China

3. School of Life Sciences, University of Dundee, Dundee, United Kingdom

4. State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

Abstract

Aspergillus fumigatus is an opportunistic fungal pathogen causing deadly infections in immunocompromised patients. Enzymes essential for fungal survival and cell wall biosynthesis are considered potential drug targets against A. fumigatus .

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

MRC programme grant

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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