Impact of Antibiotic Gut Exposure on the Temporal Changes in Microbiome Diversity-Reference-Cited by-同舟云学术

Impact of Antibiotic Gut Exposure on the Temporal Changes in Microbiome Diversity

Published:2019-10 Issue:10 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Burdet Charles¹²,Nguyen Thu Thuy¹,Duval Xavier¹²,Ferreira Stéphanie³,Andremont Antoine¹,Guedj Jérémie¹,Mentré France¹²,

Affiliation:

1. IAME, INSERM, Université de Paris, Paris, France

2. AP-HP, Bichat Hospital, Département d’Epidémiologie, Biostatistique et Recherche Clinique, Paris, France

3. Genoscreen, Lille, France

Abstract

Although the global deleterious impact of antibiotics on the intestinal microbiota is well known, temporal changes in microbial diversity during and after an antibiotic treatment are still poorly characterized. We used plasma and fecal samples collected frequently during treatment and up to one month after from 22 healthy volunteers assigned to a 5-day treatment by moxifloxacin ( n = 14) or no intervention ( n = 8).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00820-19

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