Surface Proteins and Exotoxins Are Required for the Pathogenesis of Staphylococcus aureus Pneumonia-Reference-Cited by-同舟云学术

Surface Proteins and Exotoxins Are Required for the Pathogenesis of Staphylococcus aureus Pneumonia

Published:2007-02 Issue:2 Volume:75 Page:1040-1044
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wardenburg Juliane Bubeck¹²,Patel Ravi J.¹,Schneewind Olaf¹

Affiliation:

1. Departments of Microbiology

2. Pediatrics, University of Chicago, Chicago, Illinois 60637

Abstract

ABSTRACT A model of Staphylococcus aureus -induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.01313-06

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