The ArcAB Two-Component System: Function in Metabolism, Redox Control, and Infection-Reference-Cited by-同舟云学术

The ArcAB Two-Component System: Function in Metabolism, Redox Control, and Infection

Published:2022-06-15 Issue:2 Volume:86 Page:
ISSN:1092-2172
Container-title:Microbiology and Molecular Biology Reviews
language:en
Short-container-title:Microbiol Mol Biol Rev

Author:

Brown Aric N.¹^ORCID,Anderson Mark T.¹^ORCID,Bachman Michael A.¹²^ORCID,Mobley Harry L. T.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

2. Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA

Abstract

ArcAB, also known as the Arc system, is a member of the two-component system family of bacterial transcriptional regulators and is composed of sensor kinase ArcB and response regulator ArcA. In this review, we describe the structure and function of these proteins and assess the state of the literature regarding ArcAB as a sensor of oxygen consumption.

Funder

American Heart Association

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Link

https://journals.asm.org/doi/pdf/10.1128/mmbr.00110-21

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