Affiliation:
1. Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, Yusong-gu, Taejon 305-701, Korea
Abstract
ABSTRACT
Fermentation strategies for the production of poly(3-hydroxybutyrate) (PHB) from whey by recombinant
Escherichia coli
strain CGSC 4401 harboring the
Alcaligenes latus
polyhydroxyalkanoate (PHA) biosynthesis genes were developed. The pH-stat fed-batch cultures of
E. coli
CGSC 4401 harboring pJC4, a stable plasmid containing the
A. latus
PHA biosynthesis genes, were carried out with a concentrated whey solution containing 280 g of lactose equivalent per liter. Final cell and PHB concentrations of 119.5 and 96.2 g/liter, respectively, were obtained in 37.5 h, which resulted in PHB productivity of 2.57 g/liter/h.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
167 articles.
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