A <i>Yersinia</i> T6SS Effector YezP Engages the Hemin Uptake Receptor HmuR and ZnuABC for Zn <sup>2+</sup> Acquisition-Reference-Cited by-同舟云学术

A Yersinia T6SS Effector YezP Engages the Hemin Uptake Receptor HmuR and ZnuABC for Zn ²⁺ Acquisition

Published:2023-07-26 Issue:7 Volume:89 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Liu Hai¹²,Wei Zhiyan²,Li Jiali²,Liu Xingyu³,Zhu Lingfang²,Wang Yao²,Wang Tietao⁴,Li Changfu²,Shen Xihui²^ORCID

Affiliation:

1. Qingyang Longfeng Sponge City Construction Management & Operation Co., Ltd, Qingyang, Gansu, China

2. State Key Laboratory of Crop Stress Biology for Arid Areas, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China

3. State Key Laboratory of Geological Processes and Mineral Resources, Institute of Earth Sciences, China University of Geosciences, Beijing, China

4. Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, Shaanxi, China

Abstract

Identifying the transporters involved in import of metal ions under normal physiological growth conditions in bacterial pathogens will clarify its pathogenic mechanism. Y. pseudotuberculosis YPIII, a common foodborne pathogen that infects animals and humans, uptake zinc via the T6SS4 effector YezP. However, the outer and inner transports involved in Zn 2+ acquisition remain unknown.

Funder

MOST | National Key Research and Development Program of China

MOST | National Natural Science Foundation of China

Comprehensive treatment of Xiaokongtong Gully Project

Young Talent Support Program of Shaanxi Province University

Ph. D stand-up fund of Northwest A & F University

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00240-23

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