Role of Nitric Oxide and Flavohemoglobin Homolog Genes in Aspergillus nidulans Sexual Development and Mycotoxin Production-Reference-Cited by-同舟云学术

Role of Nitric Oxide and Flavohemoglobin Homolog Genes in Aspergillus nidulans Sexual Development and Mycotoxin Production

Published:2011-08 Issue:15 Volume:77 Page:5524-5528
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Baidya Sachin¹,Cary Jeffrey W.²,Grayburn W. Scott¹,Calvo A. M.¹

Affiliation:

1. Department of Biological Sciences, Northern Illinois University, DeKalb, Illinois

2. Southern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, New Orleans, Louisiana

Abstract

ABSTRACT Flavohemoglobins are widely distributed in both prokaryotes and eukaryotes. These proteins are involved in reducing nitric oxide levels. Deletion of the Aspergillus nidulans flavohemoglobin gene fhbA induced sexual development and decreased sterigmatocystin production. Supplementation with a nitric oxide-releasing compound promoted cleistothecial formation and increased nsdD and steA expression, indicating that nitric oxide induces sexual development. This is the first study on the effect of nitric oxide on morphogenesis and secondary metabolism in fungi.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00638-11

Reference31 articles.

1. Mycotoxins

2. Regulation of aflatoxin biosynthesis;Cary J. W.;J. Toxicol. Toxin Rev.,2008

3. Yeast Flavohemoglobin, a Nitric Oxide Oxidoreductase, Is Located in Both the Cytosol and the Mitochondrial Matrix

4. Nitric oxide and iron proteins;Cooper C. E;Biochim. Biophys. Acta,1999

5. Role for the Salmonella flavohemoglobin in protection from nitric oxide;Crawford M. J.;J. Biol. Chem.,1998

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