Time to peak serum antibody response to influenza vaccine

Author:

Rastogi S1,Gross P A1,Bonelli J1,Dran S1,Levandowski R A1,Russo C1,Weksler M E1,Kaye D1,Levison M1,Abrutyn E1

Affiliation:

1. Department of Internal Medicine, Hackensack Medical Center, New Jersey 07601.

Abstract

The time to the appearance of a peak serum antibody response to influenza virus vaccine is not clearly defined. We compared the most commonly used time intervals described in the literature--4 and 6 weeks after vaccination. We studied 118 elderly patients from three different geographic sites. The 1992 to 1993 trivalent inactivated influenza virus vaccine containing influenza virus A/Beijing/353/89 (H3N2), influenza virus A/Texas/36/91 (H1N1), and influenza virus B/Panama/45/90 was used. No statistically significant differences were found at the 4- and 6-week intervals after vaccination.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference8 articles.

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4. A controlled double blind comparison of reactogenicity and protective efficacy of whole virus and split product influenza vaccines in children;Gross P. A.;J. Infect. Dis.,1977

5. Association of influenza immunization with reduction in mortality in an elderly population: a prospective study;Gross P. A.;Arch. Intern. Med.,1988

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