Time to peak serum antibody response to influenza vaccine in the elderly

Author:

Gross P A1,Russo C1,Teplitzky M1,Dran S1,Cataruozolo P1,Munk G1

Affiliation:

1. Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA.

Abstract

The earliest time at which serum antibody peaks following administration of influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 2 and 4 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91(H1N1), A/Shangdong/9/93(H3N2), and B/Panama/45/90 was used. The hemagglutination inhibition antibody titers at 2 weeks after vaccination were identical to the hemagglutination inhibition antibody titers at 4 weeks for all three vaccine components.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference8 articles.

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3. Evans A. S. 1973. Influenza and other respiratory infections p. 69-81. In J. R. Paul and C. White (ed.) Serological epidemiology. Academic Press New York.

4. Hong Kong influenza immunity: three years after immunization;Foy H. M.;JAMA,1973

5. Neutralization test in influenza: use in individuals without hemagglutination inhibition antibody;Gross P. A.;J. Clin. Microbiol.,1979

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