Bacteremia in an Immunocompromised Patient Caused by a Commensal Neisseria meningitidis Strain Harboring the Capsule Null Locus ( cnl )-Reference-Cited by-同舟云学术

Bacteremia in an Immunocompromised Patient Caused by a Commensal Neisseria meningitidis Strain Harboring the Capsule Null Locus ( cnl )

Published:2004-07 Issue:7 Volume:42 Page:2898-2901
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Vogel Ulrich¹,Claus Heike¹,von Müller Lutz²,Bunjes Donald³,Elias Johannes¹,Frosch Matthias¹

Affiliation:

1. National Reference Laboratory for Meningococci, Institute for Hygiene and Microbiology, University of Würzburg, Würzburg

2. Institute of Microbiology and Immunology

3. Department of Internal Medicine III, University of Ulm, Ulm, Germany

Abstract

ABSTRACT We recently described the capsule null locus ( cnl ) of constitutively unencapsulated Neisseria meningitidis clonal lineages. cnl meningococci were recovered from healthy carriers at high frequency. We here report on the first case of invasive disease caused by cnl meningococci in a severely immunosuppressed patient with chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. The sequence type 845 strain was extensively typed and, furthermore, shown to be sensitive to serum bactericidal activity.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.7.2898-2901.2004

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