Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ a ]Pyrene Metabolite Profile and Its Distribution in 3D Skin-Reference-Cited by-同舟云学术

Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ a ]Pyrene Metabolite Profile and Its Distribution in 3D Skin

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Lemoine Lisa¹²^ORCID,Bayrambey Dilan³,Roloff Alexander³,Hutzler Christoph³,Luch Andreas²³,Tralau Tewes¹

Affiliation:

1. German Federal Institute for Risk Assessment, Department of Pesticides Safety, Berlin, Germany

2. Institute of Pharmacy, Department of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany

3. German Federal Institute for Risk Assessment, Department of Chemical & Product Safety, Berlin, Germany

Abstract

Exposure to xenobiotics has repeatedly been associated with adverse health effects. While the majority of reported cases relate to direct substance effects, there is increasing evidence that microbiome-dependent metabolism of xenobiotic substances likewise has direct adverse effects on the host.

Funder

German Federal Institute for Risk Assessment

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01223-21

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