Glucose Phosphotransferase System Modulates Pyruvate Metabolism, Bacterial Fitness, and Microbial Ecology in Oral Streptococci

Author:

Zeng Lin1ORCID,Walker Alejandro R.1ORCID,Burne Robert A.1ORCID,Taylor Zachary A.1ORCID

Affiliation:

1. Department of Oral Biology, University of Florida, Gainesville, Florida, USA

Abstract

Dental caries is underpinned by a dysbiotic microbiome and increased acid production. As beneficial bacteria that can antagonize oral pathobionts, oral streptococci such as S. sanguinis and S. gordonii can ferment many carbohydrates, despite their relative sensitivity to low pH.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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