Genetically Modified Ruminal Bacteria Protect Sheep from Fluoroacetate Poisoning

Author:

Gregg Keith1,Hamdorf Brenton1,Henderson Kerrin1,Kopecny Jan1,Wong Cheryl1

Affiliation:

1. Rumen Biotech, Murdoch University, Murdoch, Western Australia 6150, Australia

Abstract

ABSTRACT Four strains of Butyrivibrio fibrisolvens , transformed with a gene encoding fluoroacetate dehalogenase, maintained a combined population of 10 6 to 10 7 cells ml −1 in the rumens of test sheep. Five inoculated sheep showed markedly reduced toxicological symptoms after fluoroacetate poisoning when behavioral, physiological, and histological effects were compared with those of five uninoculated control sheep.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference13 articles.

1. Allen G. Polymerase chain reaction techniques for the study of rumen bacterial ecology and biotechnology. Ph.D. thesis. 1998 University of New England Armidale New South Wales Australia

2. Fluoroacetate poisoning in sheep.;Annison E. F.;J. Comp. Pathol.,1960

3. A stable and efficient transformation system for Butyrivibrio fibrisolvens OB156.;Beard C. E.;Curr. Microbiol.,1995

4. Chick B. Personal communication.

5. Group-specific 16S rRNA hybridization probes for determinative and community structure studies of Butyrivibrio fibrisolvens in the rumen

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3