A Nucleic Acid-Based Orthopoxvirus Vaccine Targeting the Vaccinia Virus L1, A27, B5, and A33 Proteins Protects Rabbits against Lethal Rabbitpox Virus Aerosol Challenge-Reference-Cited by-同舟云学术

A Nucleic Acid-Based Orthopoxvirus Vaccine Targeting the Vaccinia Virus L1, A27, B5, and A33 Proteins Protects Rabbits against Lethal Rabbitpox Virus Aerosol Challenge

Published:2022-02-09 Issue:3 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Mucker Eric M.¹^ORCID,Golden Joseph W.¹,Hammerbeck Christopher D.¹,Kishimori Jennifer M.²,Royals Michael³,Joselyn Mathew D.¹,Ballantyne John⁴,Nalca Aysegul⁵,Hooper Jay W.¹^ORCID

Affiliation:

1. Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA

2. Headquarters Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA

3. Consultant, Fort Collins, Colorado, USA

4. Aldevron LLC, Fargo, North Dakota, USA

5. Center for Aerobiological Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA

Abstract

The eradication of smallpox and subsequent cessation of vaccination have left a majority of the population susceptible to variola virus or other emerging poxviruses. This is exemplified by human monkeypox, as evidenced by the increase in reported endemic and imported cases over the past decades.

Funder

U.S. Department of Health and Human Services

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01504-21

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