Updating Molecular Diagnostics for Detecting Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Isolates in Blood Culture Bottles-Reference-Cited by-同舟云学术

Updating Molecular Diagnostics for Detecting Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Isolates in Blood Culture Bottles

Published:2019-11 Issue:11 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Tenover Fred C.¹,Tickler Isabella A.¹,Le Victoria M.¹,Dewell Scott¹,Mendes Rodrigo E.²,Goering Richard V.³

Affiliation:

1. Cepheid, Sunnyvale, California, USA

2. JMI Laboratories, North Liberty, Iowa, USA

3. Creighton University, Omaha, Nebraska, USA

Abstract

Molecular diagnostic tests can be used to provide rapid identification of staphylococcal species in blood culture bottles to help improve antimicrobial stewardship. However, alterations in the target nucleic acid sequences of the microorganisms or their antimicrobial resistance genes can lead to false-negative results.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01195-19

Reference34 articles.

1. Vital Signs:Epidemiology and Recent Trends in Methicillin-Resistant and in Methicillin-SusceptibleStaphylococcus aureusBloodstream Infections — United States

2. A Randomized Clinical Trial Comparing Use of Rapid Molecular Testing for Staphylococcus aureus for Patients With Cutaneous Abscesses in the Emergency Department With Standard of Care

3. Clinical Validation of the Molecular BD GeneOhm StaphSR Assay for Direct Detection of Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus in Positive Blood Cultures

4. An Antimicrobial Stewardship Program’s Impact with Rapid Polymerase Chain Reaction Methicillin‐ResistantStaphylococcus aureus/S. aureusBlood Culture Test in Patients withS. aureusBacteremia

5. Randomized Trial of Rapid Multiplex Polymerase Chain Reaction–Based Blood Culture Identification and Susceptibility Testing

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