Resistance to Bacitracin as Modulated by an Escherichia coli Homologue of the Bacitracin ABC Transporter BcrC Subunit from Bacillus licheniformis-Reference-Cited by-同舟云学术

Resistance to Bacitracin as Modulated by an Escherichia coli Homologue of the Bacitracin ABC Transporter BcrC Subunit from Bacillus licheniformis

Published:1999-10 Issue:19 Volume:181 Page:6176-6178
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Harel Yael Meller¹,Bailone Adriana¹,Bibi Eitan²

Affiliation:

1. Institut Curie, Batiment 110, Centre Universitaire, F-91405 Orsay, France,1 and

2. Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel2

Abstract

ABSTRACT A small open reading frame from the Escherichia coli chromosome, bcrC EC , encodes a homologue to the BcrC subunit of the bacitracin permease from Bacillus licheniformis . We show that disruption of the chromosomal bcrC EC gene causes bacitracin sensitivity and, conversely, that BcrC EC confers bacitracin resistance when expressed from a multicopy plasmid.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.181.19.6176-6178.1999

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