Detection and quantification of type C viral proteins in tissues and sera with an enzyme immunoassay

Author:

Schetters H,Hehlmann R,Erfle V,Ramanarayanan M

Abstract

The detection and quantification of retroviral proteins in cells, tumors, and sera by an enzyme immunoassay technique (enzyme-linked immunosorbent assay [ELISA]) is described. The ELISA technique has been applied to three viral systems: murine leukemia virus, baboon endogenous virus, and simian sarcoma virus. By detecting 0.1 nf of retroviral antigen, the sensitivity of the ELISA is comparable to that of the competition radioimmunoassay technique.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference22 articles.

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5. Shared group-specific antigen of murine and feline leukemia viruses;Geering G.;Virology,1968

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